New Bio-Electronic Uric Acid Detecting Device Fabricated By Indian Researchers

Indian researchers have fabricated a latest bio-electronic uric acid detecting device at IASST. It will be a game-changer in the field of biomedical applications.

Uric acid is an essential antioxidant that helps in maintaining human’s blood pressure stability and reduces oxidative stress. 

However, the fluctuation of uric acid levels in the body can cause several diseases like hyperuricemia, gout disease, type 2 diabetes, and hypertension, and others. 

The researchers from the Institute of Advanced Study in Science and Technology (IASST) have fabricated a new bio-electronic uric acid detecting device to address this issue.

It can be used for various applications such as wearable sensors and point-of-care diagnostics.

The Bio-Electronic Uric Acid Detecting Device is built with reduced phosphorene quantum dots, a new class of zero-dimensional functional nanostructures with the unique physicochemical & surface properties. 

The quantum dots show distinctive electrical performance in biomedical applications, making them ideal for high-performance electrical biosensors. 

The device has been tested for its current voltage and impedance responses to increased uric acid concentration, and the results show a maximum current of about 1.35 ×10-6 A with the increase in uric acid concentration.

The new bio-electronic uric acid detecting device fabricated by the researchers at IASST shows reversibility in interaction with uric acid, enabling its repeated use for sensing experiments. 

The device outperforms all currently available ones in terms of effectiveness and cost as it doesn’t require any enzymes. 

Moreover, the response of the fabricated device has been investigated with real samples like human blood serum and artificial urine, making it simple, portable, cost-effective, and easy to fabricate for detecting uric acid with a limit of about 0.809 µM.

The effectiveness and versatility of the device make it an excellent option for various applications, including wearable sensors and point-of-care diagnostics. 

The researchers’ work, led by Prof. Neelotpal Sen Sarma and his Ph.D. student Nasrin Sultana, has been published in the journal ACS Applied Electronic Materials.

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